CVC: Informed Consent

What encompasses informed consent is discussed elsewhere. Here we present complications, some with published incidence, to inform the discussion.

CVC Complications

A meta-analysis of 26 studies encompassing 4,185 CVC procedures [1] found that ultrasound reduced the following complications in adults:

Incidence w/ US (%)RR vs. LandmarksP
Cannulation failure 20.18< 0.001
Arterial puncture 1.80.25 < 0.001
Hematoma 1.60.30 < 0.001
Pneumothorax 0.10.210.014
Hemothorax 00.100.007

There are some complications not reduced by the addition of ultrasound. These rates are variable and not well established.

  • CLABSI
  • Catheter-induced thrombosis 
  • Arrhythmia
  • Venous air embolism

Reducing CLABSI

SHEA / IDSA guidelines in 2014 made the following insertion related recommendations to reduce CLABSI [2]

Level I evidence:

  • Use an alcoholic chlorhexidine antiseptic for skin preparation
  • Avoid the femoral vein for central access in obese adults when the catheter is placed under planned and controlled conditions

Level II evidence:

  • Have a process in place to ensure adherence to infection prevention practices, such as a checklist
  • Hand hygiene prior to catheter insertion / manipulation 
  • Use an all-inclusive catheter cart or kit 
  • Use US guidance for IJ catheter insertion 
  • Use maximum sterile barrier precautions

  1. Wu SY, et al. Real-time two-dimensional ultrasound guidance for central venous cannulation: a meta-analysis. Anesthesiology. 2013 Feb;118(2):361-75.
  2. Marschall J, et al. SHEA/IDSA practice recommendation. Strategies to Prevent Central Line–Associated Bloodstream Infections in Acute Care Hospitals:2014 Update. Infect Control Hosp Epidemiol. 35 (7). 2014